As the milky way runs through Puppis, there are a large number of open clusters in the constellation. Messier 46 (M46) and Messier 47 (M47) are two open clusters in the same binocular field. M47 can be seen with the naked eye under dark skies, and its brightest stars are 6th magnitude. Messier 93 (M93) is another open cluster somewhat to the south. NGC 2451 is a very bright open cluster containing the star c Puppis.
On April 18, 2006, HD 69830 (the nearest star of this constellation) was discovered to have three Neptune-mass planets, the first multi-planetary system without any Jupiter-like or Saturn-like planets. The star also hosts an asteroid belt at the region between middle planet to outer planet.
On July 4, 2007, the first extrasolar planet found in the open clusterNGC 2423, was discovered around the red giant star NGC 2423-3. The planet is 10.6 times the mass of Jupiter and orbits at 2.1 AU distance.